2023

A structure-aware hierarchical graph-based multiple instance learning framework for pt staging in histopathological image

A structure-aware hierarchical graph-based multiple instance learning framework for pt staging in histopathological image

Pathological primary tumor staging depends on contextual evidence across multiple magnifications, but dense annotation on gigapixel whole-slide images is impractical. This work introduces a structure-aware hierarchical graph-based MIL framework that progressively models cross-scale contextual information instead of treating patches independently. The method improves weakly supervised pT staging by capturing multiscale structural cues that are critical for prognosis-related classification.

Recommended citation: Shi J, Tang L, Li Y, Zhang X, Gao Z, Zheng Y, Wang C, Gong T, Li C. A structure-aware hierarchical graph-based multiple instance learning framework for pt staging in histopathological image[J]. IEEE Transactions on Medical Imaging, 2023, 42(10): 3000-3011.
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